NIDA-CTN-0031A

This was an ancillary study to CTN-0031, a randomized controlled trial of Stimulant Abuser Groups to Engage in 12-Step (STAGE-12). 219 participants from 3 sites who were randomized in the CTN-0031 study were eligible for the ancillary study, in which neurocognitive testing was performed and a blood sample was obtained for the assessment of oxidative stress/damage. The purpose of the ancillary study was to replicate the finding that performance on the Stroop color-word interference task is predictive of treatment completion in participants with cocaine use disorders and to extend this finding to participants with methamphetamine use disorders. The study also evaluated performance on additional neurocognitive measures and the level of oxidative damage and the impact of each of these on stimulant use outcomes.