Because of a lapse in government funding, the information on this website may not be up to date, transactions submitted via the website may not be processed, and the agency may not be able to respond to inquiries until appropriations are enacted. The NIH Clinical Center (the research hospital of NIH) is open. For more details about its operating status, please visit cc.nih.gov. Updates regarding government operating status and resumption of normal operations can be found at opm.gov.

NIDA-MDS-0004

Division

DTMC

HEAL Study

Investigator(s)

Domenic Ciraulo, M.D.

Title

Phase 2, Double-Blind, Placebo-Controlled Trial Of Modafinil For The Treatment Of Cocaine Dependence

Short Description

To evaluate the efficacy and safety of modafinil relative to placebo in reducing cocaine use in subjects with cocaine dependence as assessed by self-report confirmed with urine assays for benzoylecgonine (BE).

Release Date

Sep 02, 2015

Description

The primary objective of this study is to evaluate the efficacy of modafinil relative to placebo in increasing the weekly mean proportion of cocaine non-use days over the treatment period as determined by self-report of cocaine use confirmed with urine assays for BE.

Keywords

Assessments

Addiction Severity Index Lite

Brief Substance Craving Scale

Clinical Global Impression Scales

Cocaine Craving Questionnaire - Now

Cocaine Selective Severity Assessment

HIV Risk-Taking Behaviour Scale