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NIDA-CPU-0016

Division

DTMC

HEAL Study

Investigator(s)

Eugene Somoza, M.D.

Title

Double-Blind, Placebo-Controlled Assessment Of Potential Interactions Between Intravenous Methamphetamine And Osmotic-Release Methylphenidate (Oros-Mph)

Short Description

This is a human inpatient clinical pharmacology study to assess potential interactions between intravenous (i.v.) methamphetamine infusion and oral osmotic release methylphenidate (OROS-MPH).

Release Date

Dec 04, 2014

Description

The primary objective of this study is to determine the safety of the OROS-MPH concurrent with i.v. d-methamphetamine infusions of 15 mg and 30 mg. Safety outcome measures include cardiovascular responses [heart rate (HR), blood pressure (BP), and electrocardiograph (ECG) measurements], oral temperature, adverse events (AEs), and clinical laboratory analyses.

Keywords

Assessments

Addiction Research Center Inventory

Subjective Drug Value

Visual Analog Scales