NIDA-CTN-0001

Division
Investigator(s)
Title
Buprenorphine/Naloxone versus Clonidine for Inpatient Opiate Detoxification
Short Description
To test the utility of Buprenorphine/Naloxone in short term (13 day) detoxification versus Clonidine in an inpatient setting.
Release Date
May 08, 2006
Description

For decades clinicians have been frustrated by the inability to successfully detoxify opiate addicted patients because opiate-based detoxification, one of the most effective means to achieving that goal, has been unavailable outside the very restrictive confines of narcotic treatment programs (NTPs). A new medication, buprenorphine, shows promise as an effective aid for opiate detoxification. However, little data have been generated for the shorter-term use of buprenorphine/naloxone for this indication. Since the diversity of clinics in the CTN provides an unparalleled opportunity to conduct such a clinical endeavor, the utility of buprenorphine/naloxone in short term (13 day) detoxification versus clonidine in an inpatient setting will be tested in the CTN.

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