NIDA-CTN-0030

Patients with prescription opioid dependence may be able to benefit from pharmacological treatments shown to be effective in heroin addicts. Clinical research has established BUP as a safe and effective alternative to methadone. The primary objective of this study is to determine whether the addition of individual drug counseling to the prescription of buprenorphine/naloxone along with Standard Medical Management for subjects dependent on prescription opioid analgesics improves outcome both during a) an initial four-week treatment with taper and b) a 12-week stabilization treatment for those who do not respond successfully to the initial treatment with taper.