NIDA-CTN-0046

This was a randomized, controlled trial in which 538 participants were recruited from 12 sites to participate in a study comparing treatment as usual plus smoking-cessation (TAU+SCT) to substance abuse treatment as usual alone (TAU). The purpose of this study was to evaluate whether concurrent smoking-cessation treatment improves, worsens, or has no effect on stimulant-use outcomes in smokers who are in outpatient substance-abuse treatment for cocaine or methamphetamine dependence. The study also evaluated: 1. the impact of TAU+SCT, relative to TAU, on other drug-abuse outcomes; 2. the efficacy of TAU+SCT, relative to TAU, in improving smoking outcomes; and 3. whether achieving complete smoking abstinence is associated with improved stimulant use outcomes.