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NIDA-CTN-0101
Division
              
          HEAL Study
              
          Investigator(s)
          
      Title 
              Subthreshold Opioid Use Disorder Prevention (STOP) Trial
          Short Description
              The Subthreshold Opioid Use Disorder Prevention (STOP) trial will test the efficacy of a primary care intervention to reduce opioid use and overdose risk, and prevent progression to OUD, in adults with unhealthy use of illicit or prescribed opioids
          Release Date
              Oct 27, 2025
          Description
              A cluster-randomized trial, conducted in 5 primary care sites, with 100 PCPs and 300adult primary care patients, will test the efficacy of STOP versus enhanced usual care (EUC). The STOP intervention, if proven efficacious, will provide a solution to preventing OUD among patients who are most at risk, thus addressing a key aspect of the current opioid crisis
          Keywords
          
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