NIDA-CTN-0044

This was a randomized, controlled trial in which 507 participants in outpatient treatment for substance use disorders were recruited from ten sites to participate in a study comparing 1) treatment as usual (TAU) to 2) a modification of TAU, which included access to the Therapeutic Education System (TES), a computerized psychosocial intervention which combines skill building modules based on the Community Reinforcement Approach (CRA) with incentives contingent upon abstinence from drugs and completion of TES modules. The purpose of this study was to evaluate the relative effectiveness of the interventions on the primary outcomes of a) drug abstinence during active treatment and b) treatment retention. The study also evaluated a number of secondary outcome measures.