Alcohol, Smoking and Substance Involvement Screening Test

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Abbreviation
ASSIST
Description

The ASSIST is an 8-item questionnaire developed by an international group of substance abuse researchers for the World Health Organization. It's purpose is to detect psychoactive substance use and related problems among primary care patients. The ASSIST provides information about: the substances people have ever used in their lifetime; the substances they have used in the past three months; problems related to substance use; risk of current or future harm; level of dependence; and injecting drug use. Substances addressed include: tobacco, alcohol, cannabis, cocaine, amphetamine type stimulants, sedatives, hallucinogens, inhalants, opioids, and other drugs.

Category
Substance Use
Subcategory
Tobacco
Alcohol
Drugs

Composite International Diagnositc Interview - Substance Abuse Module

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Abbreviation
CIDI-SAM
Description

The SAM is an expanded and more detailed version of the substance use section of the CIDI. The four diagnostic sections cover tobacco, alcohol, drugs, and caffeine. The drug section include amphetamines and other stimulants, cannabinoids, cocaine, PCP and other hallucinogens, inhalants, heroin and other opiates, barbiturates and other sedatives and tranquilizers. The SAM includes questions about onset and recency of specific symptoms, as well as the specific withdrawal symptoms and physical, social, and psychological consequences for each category of substances used. Also included are the quantity and frequency of both the heaviest and past 12 month use, and ages associated with use and remission. The SAM also assesses the respondent’s impairment and treatment seeking.

Category
Substance Use
Subcategory
Tobacco
Alcohol
Drugs

HIV Screening

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Abbreviation
HIV-Screen
Description

Ag&Ab enzyme immunoassay for qualitative determination of antigens or antibodies to HIV type 1 and/or type 2 in serum or plasma; and HIV-reactive IgG and IgM test using whole blood, serum, or plasma.

Category
Clinical Measures

CD4 T-cell Count

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Abbreviation
CD4-Test
Description

Blood specimens sent to lab for CD4 testing using plasma samples; or on-site via PIMA POC CD4 analyzer (Alere Healthcare, USA) using venous whole blood samples.

Category
Clinical Measures
Division
HEAL Study
Title
Double-blind, placebo-controlled, safety and pharmacology study with 75 mg dosage of GBR 12909 in cocaine experienced African American Volunteers.
Short Description
To assess the safety, tolerance, and pharmacokinetics of multiple dosages of 75mg oral GBR 12909 in cocaine experienced volunteers. Effects on WBC and ANC will be the primary hematology outcome measure.
Release Date
May 23, 2017
Description

This is a human laboratory study that will assess the clinical pharmacology, safety and tolerance of 75mg oral doses of GBR 12909, which is 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl) piperazine dihydrochloride, in cocaine experienced volunteers. Particular interest is being given to the hematological safety data.

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Deidentification Notes
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